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Methocarbamol must be made use of with care in people with myasthenia gravis receiving anticholinesterase brokers.

In healthy volunteers, the plasma clearance of methocarbamol ranges between 0.20 and also 0.80 L/h/kg, the mean plasma removal half-life varies in between 1 as well as 2 hrs, and the plasma healthy protein binding varies in between 46 % as well as 50 %.

Rate of treatment need to not go beyond 3 mL each minute-- i.